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David Smith, M.D.
D Best

David Smith, M.D.


From the Doctor (Sponsored)

“Surgery interested me as a great way to practice medicine and help people because it involves a more direct ‘cure’ — fixing something wrong — than, say, disciplines more focused on managing chronic illnesses. From there, I chose surgical oncology as my focus because of the complexity involved and the demand for advanced skill and a complete understanding of the disease. For me, this was how I could be most effective. It has the greatest potential for curing disease and improving lives.

“What I’m after — what NTSOA is all about — is to provide each patient the best surgical care possible. I listen to patients. I relate to them on their terms… and in terms they understand. After more than 20 years as a surgeon, still one of the most important lessons experience has taught me is that empathy, understanding and personal commitment to the individual are as essential to excellent care as skill and technique.” 

When you need surgery, whether it’s specifically to treat cancer or to treat other surgical issues, the surgeon you choose matters. At North Texas Surgical Oncology Associates (NTSOA), we understand that the best outcomes depend on the skill, capabilities, knowledge, experience and commitment of your surgical team. That’s why we are dedicated to providing the highest quality care for both cancer surgery and general surgery.

We combine compassion and unwavering commitment to your needs with truly state-of-the-art surgical capabilities and know-how, including performing procedures offered few other places in North Texas. In addition, we are uncommonly thorough and detailed, affiliated with top hospitals, and able to handle even the most complex surgical cases. Because you deserve nothing less.



  • Breast Cancer
  • Liver & pancreatic tumors
  • Thyroid, parathyroid and adrenal tumors
  • Melanoma (skin cancers)
  • Sarcomas
  • Esophageal & stomach cancers
  • Colon & rectal cancer
  • Retroperitoneal & extremity sarcomas
  • Inherited cancer syndromes 


At NTSOA,  we bring the same skill, compassion and attention to detail to general surgical procedures as they do to cancer surgeries. In addition to their excellent general surgery training, both doctors performed surgeries in and out of combat for the military and for years since leaving service. As a result, they’ve been exposed to all sorts of surgical situations, including the high-pressure, high-stakes challenges of trauma. Today, they’re well known for their commitment to and record for excellent surgical outcomes for…


  • Anti-reflux (GERD) surgery
  • Abdominal surgery
  • Gallbladder removal
  • Hernia repair
  • Colon & rectal procedures
  • Breast Surgery
  • Thyroid, parathyroid and adrenal surgery
  • Pancreatic surgery 


To schedule an appointment, call 972-696-0030. You can also request an appointment using our easy online form.

Board-Certified: American Board of Surgery
Fellow: American College of Surgeons
Fellowship: Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX
Fellowship: Surgical Critical Care and Trauma, University of North Carolina, Chapel Hill, NC
Residency: General Surgery, University of North Carolina, Chapel Hill, NC
Medical School: Uniformed Services University of the Health Sciences, F. Edward Hébert School of Medicine, Bethesda, MD
Certifications/Awards: Legion of Merit, Bronze Star, Paul Meyer Award for Best Air Force Physician, Gold Headed Cane Award
Member: Society of Surgical Oncology, American Society of Breast Surgeons, American Society of Clinical Oncology, Americas Hepato-Pancreato-Biliary Association, Society for Surgery of the Alimentary Tract, Society of Laparoendoscopic Surgeons

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Multiple Locations

  • Plano 4001 W. 15th St. Ste. 425 Plano, TX 75093
  • Frisco 5680 Frisco Square Boulevard Ste. 2200 Frisco, TX 75034
  • Irving-Las Colinas 6750 North MacArthur Boulevard Ste. 257 Irving, TX 75039
  • Plano 3801 West 15th Street Ste. 150B Plano, TX 75075
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